No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer.

NGAL/lipocalin-2 is a siderophore-binding protein that is highly expressed in several cancers. It is suggested to confer a proliferative advantage to cancer cells. Its expression has been correlated with aggressiveness of breast cancer as determined both in patients and in mouse breast cancer models...

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Main Authors: Elisabeth P Cramer, Andreas Glenthøj, Mattias Häger, Anna Juncker-Jensen, Lars H Engelholm, Eric Santoni-Rugiu, Leif R Lund, Ole D Laerum, Jack B Cowland, Niels Borregaard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3380857?pdf=render