DUX Hunting—Clinical Features and Diagnostic Challenges Associated with <i>DUX4</i>-Rearranged Leukaemia

DUX Hunting—Clinical Features and Diagnostic Challenges Associated with <i>DUX4</i>-Rearranged Leukaemia

<i>DUX4</i>-rearrangement (<i>DUX4r</i>) is a recently discovered recurrent genomic lesion reported in 4–7% of childhood B cell acute lymphoblastic leukaemia (B-ALL) cases. This subtype has favourable outcomes, especially in children and adolescents treated with intensive che...

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Bibliographic Details
Main Authors: Jacqueline A. Rehn, Matthew J. O'Connor, Deborah L. White, David T. Yeung
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
acute lymphoblastic leukaemia
<i>DUX4</i>
<i>ERG</i>
molecular subtype
Online Access:https://www.mdpi.com/2072-6694/12/10/2815

Internet

https://www.mdpi.com/2072-6694/12/10/2815

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