Receptor binding domain of SARS‐CoV‐2 from Wuhan strain to Omicron B.1.1.529 attributes increased affinity to variable structures of human ACE2

Receptor binding domain of SARS‐CoV‐2 from Wuhan strain to Omicron B.1.1.529 attributes increased affinity to variable structures of human ACE2

Background: COVID-19 is an infectious disease declared as a global pandemic caused by SARS-CoV-2 virus. Genomic changes in the receptor binding domain (RBD) region of SARS‐CoV‐2 led to an increased, infectivity in humans through interaction with the angiotensin-converting enzyme2 (ACE2) receptor. Si...

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Bibliographic Details
Main Authors: Shankargouda Patil, Khalid J. Alzahrani, Hamsa Jameel Banjer, Ibrahim Faisal Halawani, Hosam Alzahrani, Malik A. Altayar, Sarah Albogami, Robert Fua Angeles, Ali Abdel-Halim Abdel-Azim Hassan, Shilpa Bhandi, A. Thirumal Raj
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Journal of Infection and Public Health
Subjects:
SARS‐CoV‐2
Receptor binding domain
Angiotensin-converting enzyme
Omicron
Protein docking
Dynamic simulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034122001502

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http://www.sciencedirect.com/science/article/pii/S1876034122001502

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