Finding the Needle in the Haystack—the Use of Microfluidic Droplet Technology to Identify Vitamin-Secreting Lactic Acid Bacteria

Finding the Needle in the Haystack—the Use of Microfluidic Droplet Technology to Identify Vitamin-Secreting Lactic Acid Bacteria

ABSTRACT Efficient screening technologies aim to reduce both the time and the cost required for identifying rare mutants possessing a phenotype of interest in a mutagenized population. In this study, we combined a mild mutagenesis strategy with high-throughput screening based on microfluidic droplet...

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Bibliographic Details
Main Authors: Jun Chen, Mike Vestergaard, Thomas Glasdam Jensen, Jing Shen, Martin Dufva, Christian Solem, Peter Ruhdal Jensen
Format: Article
Language:English
Published: American Society for Microbiology 2017-07-01
Series:mBio
Subjects:
classical mutagenesis
droplet microfluidics
lactic acid bacteria
high-throughput screening
vitamin B2
Online Access:https://journals.asm.org/doi/10.1128/mBio.00526-17

Internet

https://journals.asm.org/doi/10.1128/mBio.00526-17

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