Lactoferrin Inhibits the Development of T2D-Induced Colon Tumors by Regulating the NT5DC3/PI3K/AKT/mTOR Signaling Pathway

Lactoferrin Inhibits the Development of T2D-Induced Colon Tumors by Regulating the NT5DC3/PI3K/AKT/mTOR Signaling Pathway

Although increasing evidence shows the association between type 2 diabetes (T2D) and colorectal cancer, the related mechanism remains unclear. This study examined the suppressive effect of lactoferrin (LF) on the development of T2D-induced colon cancer. First, a co-cultured cell model consisting of...

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Bibliographic Details
Main Authors: Huiying Li, Qianqian Yao, Chaonan Li, Linlin Fan, Haoming Wu, Nan Zheng, Jiaqi Wang
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Foods
Subjects:
type 2 diabetes (T2D)
colon cancer
lactoferrin (LF)
5′-nucleotidase domain-containing 3 (NT5DC3)
phosphorylation
Online Access:https://www.mdpi.com/2304-8158/11/24/3956

Internet

https://www.mdpi.com/2304-8158/11/24/3956

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