Efficacy and safety of a self-applied carrageenan-based gel to prevent human papillomavirus infection in sexually active young women (CATCH study): an exploratory phase IIB randomised, placebo-controlled trialResearch in context

Efficacy and safety of a self-applied carrageenan-based gel to prevent human papillomavirus infection in sexually active young women (CATCH study): an exploratory phase IIB randomised, placebo-controlled trialResearch in context

Summary: Background: Carrageenan demonstrated potent anti-HPV (human papillomavirus) activity in vitro and in animal models. The Carrageenan-gel Against Transmission of Cervical Human papillomavirus trial’s interim analysis (n = 277) demonstrated a 36% protective effect of carrageenan against incid...

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Bibliographic Details
Main Authors: Cassandra Laurie, Mariam El-Zein, Sarah Botting-Provost, Joseph E. Tota, Pierre-Paul Tellier, François Coutlée, Ann N. Burchell, Eduardo L. Franco
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:EClinicalMedicine
Subjects:
Carrageenan
Gel
HPV
Human papillomavirus
Microbicide
Randomized controlled trial
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537023002158

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http://www.sciencedirect.com/science/article/pii/S2589537023002158

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