Optical imaging of single-protein size, charge, mobility, and binding

Protein identification at the single-molecule level is the ultimate goal for biological research and disease diagnosis. Here, the authors identify the size, charge, mobility, and binding of individual protein molecules by measuring the optical and electrical responses of each protein molecule tether...

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Bibliographic Details
Main Authors: Guangzhong Ma, Zijian Wan, Yunze Yang, Pengfei Zhang, Shaopeng Wang, Nongjian Tao
Format: Article
Language:English
Published: Nature Portfolio 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18547-w