Nanoparticle-mediated selective Sfrp-1 silencing enhances bone density in osteoporotic mice
Abstract Osteoporosis (OP) is characterized by a loss in bone mass and mineral density. The stimulation of the canonical Wnt/β-catenin pathway has been reported to promote bone formation, this pathway is controlled by several regulators as secreted frizzled-related protein-1 (Sfrp-1), antagonist of...
| Autors principals: | , , , , , , , |
|---|---|
| Format: | Article |
| Idioma: | English |
| Publicat: |
BMC
2022-10-01
|
| Col·lecció: | Journal of Nanobiotechnology |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s12951-022-01674-5 |