Coumarin derivatives against amyloid-beta 40 – 42 peptide and tau protein

Coumarin derivatives against amyloid-beta 40 – 42 peptide and tau protein

In preclinical studies, simple coumarins (scoparone, limettin) and furanocoumarins (imperatorin, xanthotoxin, bergapten) have already found to demonstrate procognitive abilities. This suggests that they hold antioxidative, anti-inflammatory and inhibitory action towards acetylcholinesterase activiti...

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Bibliographic Details
Main Authors: Kowalczyk Joanna, Skalicka-Wozniak Krystyna, Budzynska Barbara, Sayed Nesrine El, Espargaró Alba, Sabate Raimon
Format: Article
Language:English
Published: Sciendo 2022-08-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
neurodegeneration
tau
aβ40/42
in vitro
in cellulo
coumarins
Online Access:https://doi.org/10.2478/cipms-2022-0013

Internet

https://doi.org/10.2478/cipms-2022-0013

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