Melatonin Moderates the Triangle of Chronic Pain, Sleep Architecture and Immunometabolic Traffic

Melatonin Moderates the Triangle of Chronic Pain, Sleep Architecture and Immunometabolic Traffic

Preclinical as well as human studies indicate that melatonin is essential for a physiological sleep state, promotes analgesia and is involved in immunometabolic signaling by regulating neuroinflammatory pathways. Experimental and clinical neuromodulation studies for chronic pain treatment suggest th...

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Bibliographic Details
Main Authors: Shafqat R. Chaudhry, Andreas Stadlbauer, Michael Buchfelder, Thomas M. Kinfe
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
melatonin
chronic pain
sleep
immune-metabolism
central and peripheral neuroinflammation pathways
augmentation of neurostimulation therapies
Online Access:https://www.mdpi.com/2227-9059/9/8/984

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https://www.mdpi.com/2227-9059/9/8/984

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