Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells

<p>Abstract</p> <p>Genomic instability is a common feature of cancer etiology. This provides an avenue for therapeutic intervention, since cancer cells are more susceptible than normal cells to DNA damaging agents. However, there is growing evidence that the epigenetic mechanisms t...

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Bibliographic Details
Main Authors: Rajendran Praveen, Ho Emily, Williams David E, Dashwood Roderick H
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Clinical Epigenetics
Subjects:
Online Access:http://www.clinicalepigeneticsjournal.com/content/3/1/4