Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

<p>Abstract</p> <p>Although nutrients, including amino acids and their metabolites such as serotonin (5-HT), are strong modulators of anxiety-related behavior, the metabolic pathway(s) responsible for this physiological modulation is not fully understood. Regarding tryptophan (Trp)...

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Bibliographic Details
Main Authors: Kanai Masaaki, Funakoshi Hiroshi, Takahashi Hisaaki, Hayakawa Tomoko, Mizuno Shinya, Matsumoto Kunio, Nakamura Toshikazu
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Molecular Brain
Online Access:http://www.molecularbrain.com/content/2/1/8