Effects of sex and deletion of neuropeptide Y2 receptors from GABAergic neurons on affective and alcohol drinking behaviors in mice

A large literature has demonstrated that neuropeptide Y (NPY) regulates many emotional and reward-related behaviors via its primary receptors, Y1R and Y2R. Classically, NPY actions at postsynaptic Y1R decrease anxiety, depression, and alcohol drinking, while its actions at presynaptic Y2R produce t...

Full description

Bibliographic Details
Main Authors: Nora M McCall, Gretchen M Sprow, Eric eDelpire, Todd E Thiele, Thomas L Kash, Kristen E Pleil
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Integrative Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnint.2013.00100/full