Recording Sodium Self-Inhibition of Epithelial Sodium Channels Using Automated Electrophysiology in <i>Xenopus</i> Oocytes

Recording Sodium Self-Inhibition of Epithelial Sodium Channels Using Automated Electrophysiology in <i>Xenopus</i> Oocytes

The epithelial sodium channel (ENaC) is a key regulator of sodium homeostasis that contributes to blood pressure control. ENaC open probability is adjusted by extracellular sodium ions, a mechanism referred to as sodium self-inhibition (SSI). With a growing number of identified ENaC gene variants as...

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Bibliographic Details
Main Authors: Rene Y. Lawong, Fabian May, Etang C. Etang, Philipp Vorrat, Jonas George, Julia Weder, Dagmar Kockler, Matthias Preller, Mike Althaus
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Membranes
Subjects:
ENaC
sodium self-inhibition
hypertension
two-electrode voltage clamp
automated electrophysiology
Online Access:https://www.mdpi.com/2077-0375/13/5/529

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https://www.mdpi.com/2077-0375/13/5/529

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