Modeling and Simulation of Process Technology for Nanoparticulate Drug Formulations—A Particle Technology Perspective

Modeling and Simulation of Process Technology for Nanoparticulate Drug Formulations—A Particle Technology Perspective

Crystalline organic nanoparticles and their amorphous equivalents (ONP) have the potential to become a next-generation formulation technology for dissolution-rate limited biopharmaceutical classification system (BCS) class IIa molecules if the following requisites are met: (i) a quantitative underst...

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Bibliographic Details
Main Authors: Jens Uhlemann, Holger Diedam, Werner Hoheisel, Tobias Schikarski, Wolfgang Peukert
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Pharmaceutics
Subjects:
nanocrystal
poorly soluble drug
precipitation
comminution
oral bioavailability
modeling and simulation
Online Access:https://www.mdpi.com/1999-4923/13/1/22

Internet

https://www.mdpi.com/1999-4923/13/1/22

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