Intra- and Inter-individual Differences in the Human Intestinal Microbial Conversion of (-)-Epicatechin and Bioactivity of Its Major Colonic Metabolite 5-(3′,4′-Dihydroxy-Phenyl)-γ-Valerolactone in Regulating Nrf2-Mediated Gene Expression

Intra- and Inter-individual Differences in the Human Intestinal Microbial Conversion of (-)-Epicatechin and Bioactivity of Its Major Colonic Metabolite 5-(3′,4′-Dihydroxy-Phenyl)-γ-Valerolactone in Regulating Nrf2-Mediated Gene Expression

(-)-Epicatechin (EC) is one of the most popular polyphenols present in various food products in daily life. Upon intake, it is intensively metabolized by microbiota in the large intestine. In the present study, intra- and inter-individual variations in this gut microbial conversion of EC and the con...

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Bibliographic Details
Main Authors: Chen Liu, Sjef Boeren, Ivonne M. C. M. Rietjens
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Nutrition
Subjects:
(-)-Epicatechin
inter-individual difference
intra-individual difference
microbial conversion
Nrf2
5-(3′
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.910785/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.910785/full

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