Mechanochemical modeling of dynamic microtubule growth involving sheet-to-tube transition.

Microtubule dynamics is largely influenced by nucleotide hydrolysis and the resultant tubulin configuration changes. The GTP cap model has been proposed to interpret the stabilizing mechanisms of microtubule growth from the view of hydrolysis effects. Besides, the growth of a microtubule involves th...

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Bibliographic Details
Main Authors: Xiang-Ying Ji, Xi-Qiao Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3243706?pdf=render