Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.

Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.

Cardiac remodelling and contractile dysfunction occur during both acute and chronic disease processes including the accumulation of insoluble aggregates of misfolded amyloid proteins that are typical features of Alzheimer's, Parkinson's and Huntington's disease (HD). While HD has been...

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Bibliographic Details
Main Authors: Michal Mielcarek, Linda Inuabasi, Marie K Bondulich, Thomas Muller, Georgina F Osborne, Sophie A Franklin, Donna L Smith, Andreas Neueder, Jim Rosinski, Ivan Rattray, Andrea Protti, Gillian P Bates
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4125112?pdf=render

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http://europepmc.org/articles/PMC4125112?pdf=render

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