AMPK integrates metabolite and kinase-based immunometabolic control in macrophages

AMPK integrates metabolite and kinase-based immunometabolic control in macrophages

Objective: Previous mechanistic studies on immunometabolism have focused on metabolite-based paradigms of regulation, such as itaconate. Here, we, demonstrate integration of metabolite and kinase-based immunometabolic control by AMP kinase. Methods: We combined whole cell quantitative proteomics wit...

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Bibliographic Details
Main Authors: Iain R. Phair, Raid B. Nisr, Andrew J.M. Howden, Magdalena Sovakova, Noor Alqurashi, Marc Foretz, Douglas Lamont, Benoit Viollet, Graham Rena
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Molecular Metabolism
Subjects:
AMPK
Metformin
A769662
Macrophages
Immunometabolism
Itaconate
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822002307

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http://www.sciencedirect.com/science/article/pii/S2212877822002307

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