Plasma Glycosaminoglycans in Children with Juvenile Idiopathic Arthritis Being Treated with Etanercept as Potential Biomarkers of Joint Dysfunction

Plasma Glycosaminoglycans in Children with Juvenile Idiopathic Arthritis Being Treated with Etanercept as Potential Biomarkers of Joint Dysfunction

We assessed the effect of two-year etanercept (ETA) therapy on the metabolism of the cartilage extracellular matrix (ECM) in patients with juvenile idiopathic arthritis (JIA). Methods: We performed a quantitative evaluation of glycosaminoglycans (GAGs) (performed by the multistage extraction and pur...

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Bibliographic Details
Main Authors: Magdalena Wojdas, Klaudia Dąbkowska, Kornelia Kuźnik-Trocha, Grzegorz Wisowski, Iwona Lachór-Motyka, Katarzyna Komosińska-Vassev, Krystyna Olczyk, Katarzyna Winsz-Szczotka
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomedicines
Subjects:
juvenile idiopathic arthritis
extracellular matrix
etanercept
cartilage turnover biomarkers
matrix metalloproteinases
Online Access:https://www.mdpi.com/2227-9059/10/8/1845

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https://www.mdpi.com/2227-9059/10/8/1845

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