Canine population structure: assessment and impact of intra-breed stratification on SNP-based association studies.

Canine population structure: assessment and impact of intra-breed stratification on SNP-based association studies.

In canine genetics, the impact of population structure on whole genome association studies is typically addressed by sampling approximately equal numbers of cases and controls from dogs of a single breed, usually from the same country or geographic area. However one way to increase the power of gene...

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Bibliographic Details
Main Authors: Pascale Quignon, Laetitia Herbin, Edouard Cadieu, Ewen F Kirkness, Benoit Hédan, Dana S Mosher, Francis Galibert, Catherine André, Elaine A Ostrander, Christophe Hitte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2129117?pdf=render

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http://europepmc.org/articles/PMC2129117?pdf=render

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