Valproic acid increases CAR T cell cytotoxicity against acute myeloid leukemia

Valproic acid increases CAR T cell cytotoxicity against acute myeloid leukemia

The treatment of B cell malignancies has dramatically changed with the introduction of immunotherapy, especially chimeric antigen receptor T (CAR-T) cell therapy. However, only limited efficacy is observed in acute myeloid leukaemia (AML). In the study, We detected CD123 and CLL-1 expression on leuk...

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Bibliographic Details
Main Authors: Ting Yang, Jingjing Wen, Yanxin Chen, Jiajie Yang, Chunye Dai, Shenjie Yu, Wenting Zhong, Lilin Liu, Chengguanng He, Wenmin Zhang, Lingfeng Liu, Jianda Hu
Format: Article
Language:English
Published: BMJ Publishing Group 2023-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/7/e006857.full

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https://jitc.bmj.com/content/11/7/e006857.full

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