Functional analysis and regulation of purified connexin hemichannels

Gap-junction channels (GJCs) are aqueous channels that communicate adjacent cells. They are formed by head-to-head association of two hemichannels (HCs), one from each of the adjacent cells. Functional HCs are connexin hexamers composed of one or more connexin isoforms. Deafness is the most frequent...

Full description

Bibliographic Details
Main Authors: Mariana C Fiori, Luis eReuss, Luis G Cuello, Guillermo A Altenberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00071/full