Ketoconazole- and fluconazole-induced embryotoxicity and skeletal anomalies in wistar rats: a comparative study

Ketoconazole and fluconazole are two broad-spectrum azole antifungals used for the treatment of superficial and systemic mycoses. Embryotoxicity and teratogenicity have been reported in some studies when those drugs are administered at high doses to pregnant rats. The aim of this study was to presen...

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Bibliographic Details
Main Authors: Vanessa Cristiane de Santana Amaral, Guilhermino Pereira Nunes Junior
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2008-12-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000600010