Increased Immunogenicity of a Minimally Immunogenic Tumor after Cancer-Targeting Near Infrared Photoimmunotherapy

Increased Immunogenicity of a Minimally Immunogenic Tumor after Cancer-Targeting Near Infrared Photoimmunotherapy

Near-infrared photoimmunotherapy (NIR-PIT) is a highly selective cancer treatment that employs an antibody photoabsorber conjugate (APC) composed of a targeting monoclonal antibody (mAb) conjugated with a photoactivatable phthalocyanine-derivative dye. Once injected and allowed to bind to a tumor, t...

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Bibliographic Details
Main Authors: Hiroaki Wakiyama, Aki Furusawa, Ryuhei Okada, Fuyuki Inagaki, Takuya Kato, Yasuhiro Maruoka, Peter L. Choyke, Hisataka Kobayashi
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
near infrared photoimmunotherapy
non-immunogenic tumor
host anti-cancer immunity
immune checkpoint inhibitor
PD-1
Online Access:https://www.mdpi.com/2072-6694/12/12/3747

Internet

https://www.mdpi.com/2072-6694/12/12/3747

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