Inflammation promotes synucleinopathy propagation

Abstract The clinical progression of neurodegenerative diseases correlates with the spread of proteinopathy in the brain. The current understanding of the mechanism of proteinopathy spread is far from complete. Here, we propose that inflammation is fundamental to proteinopathy spread. A sequence var...

Full description

Bibliographic Details
Main Authors: Tae-Kyung Kim, Eun-Jin Bae, Byung Chul Jung, Minsun Choi, Soo Jean Shin, Sung Jun Park, Jeong Tae Kim, Min Kyo Jung, Ayse Ulusoy, Mi-Young Song, Jun Sung Lee, He-Jin Lee, Donato A. Di Monte, Seung-Jae Lee
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-022-00895-w