Reliability of DNA methylation measures using Illumina methylation BeadChip

Illumina BeadChips are widely utilized in epigenome-wide association studies (EWAS). Several studies have reported that many probes on these arrays have poor reliability. Here, we compare different pre-processing methods to improve intra-class correlation coefficients (ICC). We describe the characte...

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Bibliographic Details
Main Authors: Zongli Xu, Jack A. Taylor
Format: Article
Language:English
Published: Taylor & Francis Group 2021-05-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2020.1805692