Gene expression time-series analysis of Camptothecin effects in U87-MG and DBTRG-05 glioblastoma cell lines

Gene expression time-series analysis of Camptothecin effects in U87-MG and DBTRG-05 glioblastoma cell lines

<p>Abstract</p> <p>Background</p> <p>The clinical efficacy of camptothecin (CPT), a drug specifically targeting topoisomerase I (TopoI), is under evaluation for the treatment of malignant gliomas. Due to the high unresponsiveness of these tumours to chemotherapy, it wou...

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Bibliographic Details
Main Authors: Serra Roberto, Vaccari Monica, Horn Wolfango, Farruggia Giovanna, Mascolo Maria, Capri Miriam, Perdichizzi Stefania, D'Ario Giovanni, Quercioli Daniele, Severini Cinzia, Morandi Elena, Colacci Annamaria, Silingardi Paola
Format: Article
Language:English
Published: BMC 2008-08-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/7/1/66

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http://www.molecular-cancer.com/content/7/1/66

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