The role of gene dosage in budding yeast centrosome scaling and spontaneous diploidization.

Ploidy is the number of whole sets of chromosomes in a species. Ploidy is typically a stable cellular feature that is critical for survival. Polyploidization is a route recognized to increase gene dosage, improve fitness under stressful conditions and promote evolutionary diversity. However, the mec...

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Bibliographic Details
Main Authors: Jingjing Chen, Zhiyong Xiong, Danny E Miller, Zulin Yu, Scott McCroskey, William D Bradford, Ann M Cavanaugh, Sue L Jaspersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008911