Exposure to Iron Oxide Nanoparticles Coated with Phospholipid-Based Polymeric Micelles Induces Renal Transitory Biochemical and Histopathological Changes in Mice

Exposure to Iron Oxide Nanoparticles Coated with Phospholipid-Based Polymeric Micelles Induces Renal Transitory Biochemical and Histopathological Changes in Mice

The renal toxicity induced by the intravenously injected iron oxide nanoparticles (IONPs) encapsulated in phospholipid-based polymeric micelles was studied in CD1 mice for 2 weeks. Two doses of 5 and 15 mg of Fe/kg bodyweight of NPs or saline solution (control) were tested, and the levels of antioxi...

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Bibliographic Details
Main Authors: Mihaela Balas, Ioana Mihaela Popescu Din, Anca Hermenean, Ludmila Otilia Cinteza, Anca Dinischiotu
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Materials
Subjects:
iron oxide nanoparticles
phospholipidic micelles
oxidative stress
kidney fibrosis
Online Access:https://www.mdpi.com/1996-1944/14/10/2605

Internet

https://www.mdpi.com/1996-1944/14/10/2605

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