Propofol Inhibits Microglial Activation via miR-106b/Pi3k/Akt Axis

Propofol Inhibits Microglial Activation via miR-106b/Pi3k/Akt Axis

Propofol is an established intravenous anesthetic agent with potential neuroprotective effects. In this study, we investigated the roles and the underlying mechanisms of propofol in inhibiting the pro-inflammatory responses of microglia. Propofol significantly reduced the messenger RNA (mRNA) levels...

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Bibliographic Details
Main Authors: Jianhui Liu, Pu Ai, Yiyan Sun, Xiaoyu Yang, Chunhong Li, Yihan Liu, Xiaohuan Xia, Jialin C. Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
propofol
mir-106
microglia
neuroinflammation
lipopolysaccharide
Pi3k/Akt signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.768364/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.768364/full

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