Propofol Inhibits Microglial Activation via miR-106b/Pi3k/Akt Axis

Propofol is an established intravenous anesthetic agent with potential neuroprotective effects. In this study, we investigated the roles and the underlying mechanisms of propofol in inhibiting the pro-inflammatory responses of microglia. Propofol significantly reduced the messenger RNA (mRNA) levels...

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Détails bibliographiques
Auteurs principaux: Jianhui Liu, Pu Ai, Yiyan Sun, Xiaoyu Yang, Chunhong Li, Yihan Liu, Xiaohuan Xia, Jialin C. Zheng
Format: Article
Langue:English
Publié: Frontiers Media S.A. 2021-10-01
Collection:Frontiers in Cellular Neuroscience
Sujets:
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fncel.2021.768364/full