Site-Specific DC Surface Signatures Influence CD4+ T Cell Co-stimulation and Lung-Homing

Site-Specific DC Surface Signatures Influence CD4+ T Cell Co-stimulation and Lung-Homing

Dendritic cells (DCs) that drain the gut and skin are known to favor the establishment of T cell populations that home to the original site of DC-antigen (Ag) encounter by providing soluble “imprinting” signals to T cells in the lymph node (LN). To study the induction of lung T cell-trafficking, we...

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Bibliographic Details
Main Authors: David Pejoski, Marie Ballester, Floriane Auderset, Maria Vono, Dennis Christensen, Peter Andersen, Paul-Henri Lambert, Claire-Anne Siegrist
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
CD11b+ dendritic cells
lung CD4+ T cells
lung homing
tissue imprinting
costimulation
vaccination route
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01650/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01650/full

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