Leucosceptoside A from Devil’s Claw Modulates Psoriasis-like Inflammation via Suppression of the PI3K/AKT Signaling Pathway in Keratinocytes

Leucosceptoside A from Devil’s Claw Modulates Psoriasis-like Inflammation via Suppression of the PI3K/AKT Signaling Pathway in Keratinocytes

Psoriasis is a chronic inflammatory skin condition characterized by abnormal keratinocyte proliferation and differentiation that is accompanied with dysregulated immune response and abnormal vascularization. Devil’s claw (<i>Harpagophytum procumbens</i> (Burch.) DC. ex Meisn.) tubers ext...

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Bibliographic Details
Main Authors: Ivanka K. Koycheva, Liliya V. Mihaylova, Monika N. Todorova, Zhivka P. Balcheva-Sivenova, Kalina Alipieva, Claudio Ferrante, Giustino Orlando, Milen I. Georgiev
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
psoriasis
keratinocytes
inflammation
verbascoside
leucosceptoside A
devil’s claw
Online Access:https://www.mdpi.com/1420-3049/26/22/7014

Internet

https://www.mdpi.com/1420-3049/26/22/7014

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