Mitochondria and Doxorubicin-Induced Cardiomyopathy: A Complex Interplay

Mitochondria and Doxorubicin-Induced Cardiomyopathy: A Complex Interplay

Cardiotoxicity has emerged as a major side effect of doxorubicin (DOX) treatment, affecting nearly 30% of patients within 5 years after chemotherapy. Heart failure is the first non-cancer cause of death in DOX-treated patients. Although many different molecular mechanisms explaining the cardiac dera...

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Bibliographic Details
Main Authors: Leonardo Schirone, Luca D’Ambrosio, Maurizio Forte, Riccardo Genovese, Sonia Schiavon, Giulia Spinosa, Giuliano Iacovone, Valentina Valenti, Giacomo Frati, Sebastiano Sciarretta
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
DOX
anthracycline
cardiomyopathy
mitochondria
heart
Online Access:https://www.mdpi.com/2073-4409/11/13/2000

Internet

https://www.mdpi.com/2073-4409/11/13/2000

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