Plasmodium vivax but Not Plasmodium falciparum Blood-Stage Infection in Humans Is Associated with the Expansion of a CD8+ T Cell Population with Cytotoxic Potential.

Plasmodium vivax but Not Plasmodium falciparum Blood-Stage Infection in Humans Is Associated with the Expansion of a CD8+ T Cell Population with Cytotoxic Potential.

P. vivax and P. falciparum parasites display different tropism for host cells and induce very different clinical symptoms and pathology, suggesting that the immune responses required for protection may differ between these two species. However, no study has qualitatively compared the immune response...

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Bibliographic Details
Main Authors: Julie G Burel, Simon H Apte, James S McCarthy, Denise L Doolan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5145136?pdf=render

Internet

http://europepmc.org/articles/PMC5145136?pdf=render

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