Cryptococcal cell morphology affects host cell interactions and pathogenicity.

Cryptococcus neoformans is a common life-threatening human fungal pathogen. The size of cryptococcal cells is typically 5 to 10 microm. Cell enlargement was observed in vivo, producing cells up to 100 microm. These morphological changes in cell size affected pathogenicity via reducing phagocytosis b...

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Bibliographic Details
Main Authors: Laura H Okagaki, Anna K Strain, Judith N Nielsen, Caroline Charlier, Nicholas J Baltes, Fabrice Chrétien, Joseph Heitman, Françoise Dromer, Kirsten Nielsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20585559/pdf/?tool=EBI