Evaluation of porcine GM-CSF during PRRSV infection in vitro and in vivo indicating a protective role of GM-CSF related with M1 biased activation in alveolar macrophage during PRRSV infection

Evaluation of porcine GM-CSF during PRRSV infection in vitro and in vivo indicating a protective role of GM-CSF related with M1 biased activation in alveolar macrophage during PRRSV infection

Granulocyte-macrophage colony stimulating factor (GM-CSF), participates in diverse biological processes associated with innate and adaptive immunity, has unknown effects during PRRSV infection. Here, a double-antibody sandwich ELISA for pGM-CSF was developed in-house for evaluation of pGM-CSF level...

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Bibliographic Details
Main Authors: Qi Ji, Guanggang Qu, Bing Liu, Yang Bai, Guihua Wang, Rui Chen, Xu Zheng, Zhigang Zhang, Yonglin Yang, Chunyan Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
PRRSV
GM-CSF
macrophage activation
immune response
ELISA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.967338/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.967338/full

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