The Role of Superoxide Dismutase 1 in Amyotrophic Lateral Sclerosis: Identification of Signaling Pathways, Regulators, Molecular Interaction Networks, and Biological Functions through Bioinformatics

The Role of Superoxide Dismutase 1 in Amyotrophic Lateral Sclerosis: Identification of Signaling Pathways, Regulators, Molecular Interaction Networks, and Biological Functions through Bioinformatics

Mutations in superoxide dismutase 1 (SOD1) result in misfolding and aggregation of the protein, causing neurodegenerative amyotrophic lateral sclerosis (ALS). In recent years, several new SOD1 variants that trigger ALS have been identified, making it increasingly crucial to understand the SOD1 toxic...

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Bibliographic Details
Main Authors: Sharad Kumar Suthar, Sang-Yoon Lee
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Brain Sciences
Subjects:
superoxide dismutase 1
antioxidant
amyotrophic lateral sclerosis
canonical pathways
regulators
molecular interaction network
Online Access:https://www.mdpi.com/2076-3425/13/1/151

Internet

https://www.mdpi.com/2076-3425/13/1/151

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