Randomized study comparing full dose monotherapy (S-1 followed by irinotecan) and reduced dose combination therapy (S-1/oxaliplatin followed by S-1/irinotecan) as initial therapy for older patients with metastatic colorectal cancer: NORDIC 9

Randomized study comparing full dose monotherapy (S-1 followed by irinotecan) and reduced dose combination therapy (S-1/oxaliplatin followed by S-1/irinotecan) as initial therapy for older patients with metastatic colorectal cancer: NORDIC 9

Abstract Background Metastatic colorectal cancer (mCRC) is a disease of older age, but there is a relative lack of knowledge about effects of chemotherapy in older patients as they are under-represented in clinical trials. Little data can guide whether the strategy in older mCRC patients should be a...

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Bibliographic Details
Main Authors: Stine Braendegaard Winther, Pia Österlund, Åke Berglund, Bengt Glimelius, Camilla Qvortrup, Halfdan Sorbye, Per Pfeiffer, - on behalf of the Academy of Geriatric Cancer Research (AgeCare)
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Cancer
Subjects:
Randomized phase II
Non-intensive
SOX
IRIS
Oral
Geriatric assessment
Online Access:http://link.springer.com/article/10.1186/s12885-017-3526-8

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http://link.springer.com/article/10.1186/s12885-017-3526-8

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