Ectromelia Virus Disease Characterization in the BALB/c Mouse: A Surrogate Model for Assessment of Smallpox Medical Countermeasures

Ectromelia Virus Disease Characterization in the BALB/c Mouse: A Surrogate Model for Assessment of Smallpox Medical Countermeasures

In 2007, the United States– Food and Drug Administration (FDA) issued guidance concerning animal models for testing the efficacy of medical countermeasures against variola virus (VARV), the etiologic agent for smallpox. Ectromelia virus (ECTV) is naturally-occurring and responsible for severe mortal...

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Bibliographic Details
Main Authors: Jennifer Garver, Lauren Weber, Eric M. Vela, Mike Anderson, Richard Warren, Michael Merchlinsky, Christopher Houchens, James V. Rogers
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Viruses
Subjects:
ectromelia
BALB/c
smallpox
surrogate model
vaccine
medical countermeasure
antiviral
Online Access:http://www.mdpi.com/1999-4915/8/7/203

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http://www.mdpi.com/1999-4915/8/7/203

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