Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway

Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway

The purpose of this study is to investigate the protective effect of kaempferol (KAE), the main active monomer from Penthorum chinense Pursh, on hepatic ischemia/reperfusion injury (HI/RI) and its specific mechanism. HI/RI is a common complication closely related to the prognosis of liver surgery, a...

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Bibliographic Details
Main Authors: Yifan Chen, Tongxi Li, Peng Tan, Hao Shi, Yonglang Cheng, Tianying Cai, Junjie Bai, Yichao Du, Wenguang Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
kaempferol
ischemia/reperfusion
oxidative stress
inflammation
Nrf2/HO-1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.857015/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.857015/full

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