DeePaN: deep patient graph convolutional network integrating clinico-genomic evidence to stratify lung cancers for immunotherapy

Abstract Immuno-oncology (IO) therapies have transformed the therapeutic landscape of non-small cell lung cancer (NSCLC). However, patient responses to IO are variable and influenced by a heterogeneous combination of health, immune, and tumor factors. There is a pressing need to discover the distinc...

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Bibliographic Details
Main Authors: Chao Fang, Dong Xu, Jing Su, Jonathan R Dry, Bolan Linghu
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-021-00381-z