Directed induction of functional motor neuron-like cells from genetically engineered human mesenchymal stem cells.

Directed induction of functional motor neuron-like cells from genetically engineered human mesenchymal stem cells.

Cell replacement using stem cells is a promising therapeutic approach to treat degenerative motor neuron (MN) disorders, such as amyotrophic lateral sclerosis and spinal cord injury. Human bone marrow-derived mesenchymal stem cells (hMSCs) are a desirable cell source for autologous cell replacement...

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Bibliographic Details
Main Authors: Hwan-Woo Park, Jung-Sun Cho, Chul-Kyu Park, Sung Jun Jung, Chang-Hwan Park, Shin-Jae Lee, Seog Bae Oh, Young-Seok Park, Mi-Sook Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3320649?pdf=render

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http://europepmc.org/articles/PMC3320649?pdf=render

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