Computational Design and Development of Benzodioxane-Benzamides as Potent Inhibitors of FtsZ by Exploring the Hydrophobic Subpocket

Multidrug resistant <i>Staphylococcus aureus</i> is a severe threat, responsible for most of the nosocomial infections globally. This resistant strain is associated with a 64% increase in death compared to the antibiotic-susceptible strain. The prokaryotic protein FtsZ and the cell divis...

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Detalhes bibliográficos
Principais autores: Valentina Straniero, Victor Sebastián-Pérez, Lorenzo Suigo, William Margolin, Andrea Casiraghi, Martina Hrast, Carlo Zanotto, Irena Zdovc, Antonia Radaelli, Ermanno Valoti
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2021-04-01
coleção:Antibiotics
Assuntos:
Acesso em linha:https://www.mdpi.com/2079-6382/10/4/442