Mesenchymal stem cells induce dynamic immunomodulation of airway and systemic immune cells in vivo but do not improve survival for mice with H1N1 virus-induced acute lung injury

Mesenchymal stem cells induce dynamic immunomodulation of airway and systemic immune cells in vivo but do not improve survival for mice with H1N1 virus-induced acute lung injury

Introduction: Influenza A virus (IAV)-induced acute lung injury (ALI) is characterized by pronounced proinflammatory activation and respiratory lung dysfunction. In this study, we performed deep immune profiling on airway and circulating immune cells to examine the effect of immunomodulation and the...

Full description

Bibliographic Details
Main Authors: Yuan Tan, Yan Wang, Luciana Souza-Moreira, Chi Wang, Aidan B. P. Murray, Mahmoud Salkhordeh, Maria Florian, Lauralyn McIntyre, Duncan J. Stewart, Shirley H. J. Mei
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mesenchymal stem cells
influenza A
immunomodulation
acute lung injury
viral infection
H1N1
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1203387/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1203387/full

Similar Items