Mesenchymal stem cells induce dynamic immunomodulation of airway and systemic immune cells in vivo but do not improve survival for mice with H1N1 virus-induced acute lung injury
Introduction: Influenza A virus (IAV)-induced acute lung injury (ALI) is characterized by pronounced proinflammatory activation and respiratory lung dysfunction. In this study, we performed deep immune profiling on airway and circulating immune cells to examine the effect of immunomodulation and the...
Main Authors: | Yuan Tan, Yan Wang, Luciana Souza-Moreira, Chi Wang, Aidan B. P. Murray, Mahmoud Salkhordeh, Maria Florian, Lauralyn McIntyre, Duncan J. Stewart, Shirley H. J. Mei |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-06-01
|
Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1203387/full |
Similar Items
-
Effects of immunomodulators on the response induced by vaccines against autoimmune diseases
by: Dante J. Marciani
Published: (2017-10-01) -
Comparison of freshly cultured versus cryopreserved mesenchymal stem cells in animal models of inflammation: A pre-clinical systematic review
by: Chintan Dave, et al.
Published: (2022-07-01) -
The expression mechanism of programmed cell death 1 ligand 1 and its role in immunomodulatory ability of mesenchymal stem cells
by: Zhuo Chen, et al.
Published: (2024-01-01) -
Percutaneous Ablation-Induced Immunomodulation in Hepatocellular Carcinoma
by: Lucile Dumolard, et al.
Published: (2020-06-01) -
Regulatory role of the programmed cell death 1 signaling pathway in sepsis induced immunosuppression
by: Shubai Zhong, et al.
Published: (2023-05-01)