Colocalized, bidirectional optogenetic modulations in freely behaving mice with a wireless dual-color optoelectronic probe

Simultaneous neural activation and inhibition in the same brain region of animals is highly desirable. Here the authors report a wireless, dual-colour optogenetic probe with the co-expression of two spectrally distinct opsins to allow for bidirectional neuronal activity manipulation in a rodent mode...

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Bibliographic Details
Main Authors: Lizhu Li, Lihui Lu, Yuqi Ren, Guo Tang, Yu Zhao, Xue Cai, Zhao Shi, He Ding, Changbo Liu, Dali Cheng, Yang Xie, Huachun Wang, Xin Fu, Lan Yin, Minmin Luo, Xing Sheng
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28539-7