Mathematical modelling reveals cellular dynamics within tumour spheroids.

Tumour spheroids are widely used as an in vitro assay for characterising the dynamics and response to treatment of different cancer cell lines. Their popularity is largely due to the reproducible manner in which spheroids grow: the diffusion of nutrients and oxygen from the surrounding culture mediu...

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Bibliographic Details
Main Authors: Joshua A Bull, Franziska Mech, Tom Quaiser, Sarah L Waters, Helen M Byrne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007961