Poly(2-methyl-2-oxazoline) as a polyethylene glycol alternative for lipid nanoparticle formulation

Poly(2-methyl-2-oxazoline) as a polyethylene glycol alternative for lipid nanoparticle formulation

Lipid nanoparticles (LNPs) have emerged as the platform of choice for mRNA delivery. Polyethylene glycol (PEG) is considered a key component of currently approved LNP-based delivery systems as it ensures particle stability and shapes various facets of LNP behavior in biological systems. Whilst PEG h...

Full description

Bibliographic Details
Main Authors: Dwain George van Zyl, Livia Palmerston Mendes, Raphaela Patricia Semper, Christine Rueckert, Patrick Baumhof
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Drug Delivery
Subjects:
lipid nanoparticle (LNP)
polyethelene glycol (PEG)
poly(2-methyl-2-oxazoline) PMOZ
mRNA delivery
vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fddev.2024.1383038/full

Internet

https://www.frontiersin.org/articles/10.3389/fddev.2024.1383038/full

Similar Items